Senior Scientist, Protein Drug Product Development

Company Description:

Insmed is a global biopharmaceutical company on a mission to transform the lives of patients living with serious and rare diseases. Our most valuable resource is our employees, and everything we do is motivated by a patients-first mentality. We are dedicated to growing our team with talented individuals from around the world who are willing to challenge the status quo, solve problems, and work collaboratively with a sense of urgency and compassion.

If you share our vision and want to work with the most dedicated people in the biopharma industry, come to Insmed to accelerate your career.

Recognitions:

Consistently Ranked Science’s Top Employer

Insmed is dedicated to creating a collaborative environment where our team can thrive. Every day, our employees turn their passion for science and research into innovative solutions for patients. That’s why we’ve been named the No. 1 company to work for in the biopharma industry in Science’s Top Employers survey for four years in a row.

A Certified Great Place to Work®

We believe our company is truly special, and our employees agree. In July 2024, we became Great Place to Work-certified in the U.S. for the fourth year in a row. We are also honored to have been listed on the Best Workplaces in Biopharma™, Best Workplaces in New York™, PEOPLE® Companies That Care, Best Workplaces for Women™, Best Workplaces for Millennials™, and Best Medium Workplaces™ lists.

Insmed’s Research team seeks an experienced candidate to spearhead drug product formulation and process development, biophysical characterization, stability evaluation, and tech transfer of cutting-edge biotherapeutic candidates.

Responsibilities:

• Lead formulation and characterization support of biotherapeutic drug product discovery and development across different therapeutic areas.
• Utilize protein analytical techniques to inform on optimization of formulation and process to support development candidate nomination.
• Evaluate, select, and apply standard procedures to assess biotherapeutic stability as a function of formulation and process and lead tech transfer activities.
• Present findings in internal and external meetings, author technical reports and publications.
• Communicate with internal and external partners to progress projects.

Position Requirements (Required and/or Preferred Skills, Experience and Education):

• PhD in Biochemistry, Biotechnology, Chemical Engineering, Bioengineering, Pharmaceutical Sciences or a related field with 4+ years of relevant industry experience or MS with 8+ years of relevant hands-on experience.
• Solid understanding of biotherapeutic formulation and characterization workflows to capture standard product critical quality attributes.
• Experience developing formulations and processes to stabilize protein therapeutics.
• Experience using analytical techniques to characterize proteins including light scattering (e.g., DLS, SEC-MALS), mass photometry, circular dichroism, and thermal stability (e.g., DSC, DSF).
• Experience investigating biotherapeutic half-life extension is a plus.
• Target affinity characterization experience (e.g., ITC, SPR, BLI) is a plus.
• Protein production experience using prokaryotic and eukaryotic host systems a plus.
• Experience using automated chromatography workstations (e.g., AKTA FPLCs) and employing multi-dimensional purification strategies is a plus.
• Experience with crystallization techniques (e.g., co-crystallization, seeding, soaking, etc.) is a plus.
• A record of scientific publication employing the skills listed above.
• Familiarity with experiment documentation using electronic lab notebook.
• Strong written and oral communication skills are required.
• Applicants should be detail-oriented, highly organized, and able to multi-task with multiple projects.
• Must successfully exhibit Insmed’s five (5) core values of Collaboration, Accountability, Passion, Respect, and Integrity along with any other position specific competencies.
• Individuals must demonstrate the ability to interact successfully in a dynamic and culturally diverse workplace.

Salary Range: $115,000 - $161,867 a year

Compensation & Benefits:

At Insmed, we’re committed to investing in every team member’s total well-being, now and in the future. Our benefit programs vary by country but we offer the following to all Insmed team members, regardless of geographic location:

• Flexible approach to how we work
• Health benefits and time-off plans
• Competitive compensation package, including bonus
• Equity Awards (Long-Term Incentives)
• Employee Stock Purchase Plan (ESPP)

For more information on U.S. benefits click here.

Additional Information:

Insmed Incorporated is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.

The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement.

Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

Applications are accepted for 5 calendar days from the date posted or until the position is filled.