Principal Research Associate, in vivo Pharmacology

Job Location: 880 Winter Street, Waltham MA 02451

This position is eligible for TScan Therapeutics, Inc.s Employee Referral Program.

Job Duties:

The Principal Research Associate, in vivo Pharmacology will be responsible for the following job duties:

(1) Participate in in vivo pharmacology efforts and engage in IND-enabling activities; (2) Design and execute in vivo preclinical research focused on anti-tumor efficacy and mechanism of action studies for the companys lead therapeutic candidates; (3) Perform standard and complex in vivo procedures, such as tumor implantation and measurements (solid or liquid tumor models), multi route dosing, blood sampling, and tissue necropsy; (4) Perform standard in vitro and ex vivo work such as cell culture, tumor analysis, flow cytometry, and cytokine measurements; (5) Maintain experimental records, analyze data, and prepare study reports; and

(6) Be familiar with IACUC protocols and guidelines.

Requirements:

Employer requires a master's degree in biological science, biotechnology, or a closely related field and four (4) years of work experience as a biological scientist, or closely related occupation, conducting research and laboratory activities. In addition, the employer requires the following:

(1) Demonstrated knowledge of in vivo cancer biology, pharmacology, immunology, cell therapy, or related disciplines gained through four (4) years of work experience in a laboratory environment with a focus on cancer biology; (2) Demonstrated understanding of IACUC protocols and guidelines gained through four (4) years of work experience working with animal models of cancer; (3) Demonstrated ability in animal handling, tumor implantation and measurement, blood collection, and necropsy gained through four (4) years of work experience; and

(4) Demonstrated knowledge of flow cytometry, cell culture, or functional assays involving primary immune cells gained through three (3) years of work experience.

All years of experience may be gained concurrently.

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