Sr. Research Associate /Scientist, Analytical Chemistry/Compound Management

Overview:

The scientist will independently perform compound purity assays, including proactive and retrospective analyses of internal libraries while supporting associated compound management activities.

Responsibilities:

• Process compound requests with accuracy and efficiency using automated workflows, liquid handling tools, and sample management systems
• Prepare 384-well compound plates for follow-ups for high throughput screens, ensuring quality and timely delivery
• Maintain the integrity of the compound management process by performing quality control procedures on liquid handling equipment and troubleshooting issues
• Maintain accurate records of compound intake, distribution, and storage with LIMS
• Accurately weigh, dissolve, and transfer compound aliquots
• Closely collaborate with team members to accurately and efficiently fulfill compound distribution requests

• Key operations leader for acquisition, processing, publishing, and interpreting compound purity data (e.g., LCMS QC)
• Accurately and efficiently fulfill compound purity assessment requests from team members
• Maintain detailed internal library purity measurement records
• Regularly prepare and present data summaries to key stakeholders
• Liaise with external vendors to support the organization's analytical chemistry needs

• Work closely with the high throughput screening scientists to ensure timely delivery of compounds for screening campaigns.
• Collaborate with the Compound Management group in Basel to ensure the uniformity of processes across the organization
• Confer with team members across both sites to maintain in-house LCMS instrumentation and associated peripherals

Qualifications:

• BS or MS (or equivalent) in chemistry or related discipline
• 5~8 (BS) or 3~6 (MS) years of experience in an analytical chemistry lab setting, preferably with prior experience in the biotechnology or pharmaceutical industry
• Prior experience in acquiring, processing, and analyzing small molecule LCMS data
• Experience operating liquid handlers (e.g., Hamilton VANTAGE, Echo) and related automation instrumentation
• Excellent communication skills, including the ability to summarize large data sets to enable strategic decision-making
• Keen attention to detail and timely upkeep of accurate experimental records