Upstream Manufacturing Associate
Global Life Science Hub is partnered with an incredible biopharmaceutical company specializing in difficult-to-formulate biologics. Recently, the company has achieved 2 FDA approvals and is transitioning from R&D to a full-scale commercial organization looking to build a new state-of-the-art facility in New Jersey as they ramp up production efforts from 50L to 2000L in Q4.
We are searching for a passionate Upstream Manufacturing Associate with solid cell culture expertise to support the scale-up manufacturing efforts. The ideal candidate will have extensive experience working with CHO cells and perfusion-based bioreactor systems.
Responsibilities:
- Lead and execute upstream batches, including mammalian cell culture with a focus on CHO cell lines.
- Design, optimize, and troubleshoot cell culture processes in batch, fed-batch, and perfusion bioreactor systems.
- Maintain and scale up cell culture operations to support clinical and commercial manufacturing.
- Collaborate with cross-functional teams to transfer processes from development to GMP manufacturing.
- Perform cell culture maintenance, monitoring, and harvesting in compliance with regulatory standards.
- Analyze data, prepare technical reports, and present findings to project teams.
- Implement continuous improvements in bioprocessing techniques to enhance productivity and product quality.
- Adhere to safety and regulatory guidelines to ensure a high-quality manufacturing environment.
Experience/Qualifications:
- BSc/MSc within a life science related field with 3+ years experience in a pharma/biotech organization
- Expertise in mammalian cell culture with a focus on CHO cells
- Experience with perfusion bioreactors
- Previous background in bioreactor operations including scale-up from Clinical to Commercial
- Strong familiarity with GMP regulations
Apply:
The Global Life Science Hub are a niche Life Science headhunting firm. We place professionals across Europe and the US for a variety of Biotechnology, Pharmaceutical and CDMO companies ranging from small start-ups to large global organisations.
If you’re interested, please apply below. If this position doesn’t interest you, please visit our website for a list of more vacancies – www.glshub.com